Opportunity Information: Apply for PA 18 383
A Family-Centered Self-Management of Chronic Conditions (R01 Clinical Trial Optional) is a National Institutes of Health (NIH) discretionary grant opportunity (Funding Opportunity Number PA-18-383; CFDA 93.361) designed to strengthen the evidence base for family-centered self-management (FCSM) in the context of chronic health conditions. The core aim is to support research that advances the science behind how families, not just individual patients, can effectively manage ongoing illnesses over time. In practice, this emphasis on "family-centered" signals interest in interventions, models, measures, and implementation approaches that recognize the family or household as a key unit of care, support, decision-making, and daily disease management.
The award mechanism is an R01 research project grant, which typically supports substantial, multi-year research programs. The FOA is labeled "Clinical Trial Optional," meaning applicants may propose studies that include a clinical trial when appropriate, but a clinical trial is not required to be responsive. This allows a wide range of study designs, from foundational or mechanistic work (such as developing and validating family-centered self-management frameworks or measures) to efficacy, effectiveness, or implementation research that tests strategies for improving self-management outcomes across different chronic conditions.
Eligibility is broad and intentionally inclusive across sectors and organization types. Eligible applicants include various levels of government (state, county, city/township), special district governments, independent school districts, and public housing authorities/Indian housing authorities. Academic institutions are eligible, including public/state-controlled and private institutions of higher education. The FOA also welcomes nonprofit organizations both with and without 501(c)(3) status, for-profit organizations (other than small businesses), and small businesses. In addition, the opportunity explicitly highlights a range of "other eligible applicants" such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISI). It also includes Indian/Native American Tribal Governments that are not federally recognized, eligible federal agencies, faith-based or community-based organizations, regional organizations, U.S. territories or possessions, and even non-U.S. entities (foreign organizations), underscoring NIH's intent to encourage diverse applicant pools and research settings.
From a topic standpoint, the FOA is centered on chronic conditions broadly rather than a single disease area, which suggests the program is looking for transferable principles and evidence that can improve family-centered self-management across multiple health challenges. Projects responsive to this call would generally focus on how families acquire skills, coordinate care, communicate with clinicians, support behavior change, manage symptoms, adhere to treatment plans, handle stress and caregiving burden, and navigate health systems over long periods. Because self-management is often shaped by social context, the family-centered lens also creates space for research that addresses cultural factors, equity considerations, and the real-world constraints families face, especially in underserved or historically marginalized communities.
Key administrative details in the source information include an original closing date of January 7, 2021, and a creation date of November 21, 2017. The award ceiling and expected number of awards are not specified in the provided listing, which is common in some FOA summaries and typically means applicants should consult the full FOA text and NIH institute-specific guidance for budget expectations, project period norms, and programmatic priorities. Overall, this opportunity is positioned to fund rigorous research that helps define what effective family-centered self-management looks like, how to measure it, how to improve it, and how to support families as active partners in long-term chronic disease care.Apply for PA 18 383
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "A Family-Centered Self-Management of Chronic Conditions (R01 Clinical Trial Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.361.
- This funding opportunity was created on 2017-11-21.
- Applicants must submit their applications by 2021-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: A Family-Centered Self-Management of Chronic Conditions (R01 Clinical Trial Optional)
What is this grant opportunity?
This is a National Institutes of Health (NIH) discretionary funding opportunity titled "A Family-Centered Self-Management of Chronic Conditions (R01 Clinical Trial Optional)." The Funding Opportunity Number (FON) is PA-18-383, and the CFDA listing associated with it is 93.361.
What is the main purpose of the program?
The purpose is to strengthen the evidence base for family-centered self-management (FCSM) in chronic health conditions. The focus is on research that advances the science of how families (not only individual patients) can manage ongoing illnesses over time.
What does "family-centered self-management" mean in this context?
In this opportunity, "family-centered" signals that NIH is interested in the family or household as a key unit of care and day-to-day disease management. This can include how families support decision-making, share responsibilities, coordinate care, communicate with clinicians, and sustain management strategies over long periods.
What type of grant mechanism is used?
The award mechanism is an R01 research project grant, which is generally used to support substantial research projects that can span multiple years.
Are clinical trials required?
No. The FOA is labeled "Clinical Trial Optional," which means a clinical trial may be proposed when appropriate, but a clinical trial is not required to be responsive to the opportunity.
What kinds of research designs could be appropriate under "clinical trial optional"?
The provided description indicates the FOA can support a wide range of designs, including foundational or mechanistic work (such as developing and validating frameworks or measures for family-centered self-management) as well as efficacy, effectiveness, or implementation research that tests strategies to improve self-management outcomes.
What health topics or diseases are covered?
The FOA is centered on chronic conditions broadly rather than being limited to one disease area. This suggests interest in principles, models, measures, and evidence that can be transferable across multiple chronic health challenges.
What kinds of project topics are likely to fit this opportunity based on the description?
Projects would generally focus on how families manage chronic illness over time, including (as described): acquiring skills, coordinating care, communicating with clinicians, supporting behavior change, managing symptoms, adhering to treatment plans, handling stress and caregiving burden, and navigating health systems over long periods.
Does the opportunity support research related to culture, equity, or underserved communities?
Yes, the description notes that self-management is shaped by social context and that the family-centered lens creates space for research addressing cultural factors, equity considerations, and real-world constraints faced by families, including those in underserved or historically marginalized communities.
Who is eligible to apply?
Eligibility is broad. The description lists many eligible applicant types across government, education, nonprofit, and business sectors, including foreign (non-U.S.) entities.
Which government entities are eligible?
Eligible government applicants include state governments, county governments, city/township governments, special district governments, independent school districts, and public housing authorities/Indian housing authorities.
Are academic institutions eligible?
Yes. Eligible academic applicants include public/state-controlled institutions of higher education and private institutions of higher education.
Are nonprofit organizations eligible?
Yes. The FOA welcomes nonprofit organizations both with 501(c)(3) status and without 501(c)(3) status.
Are for-profit organizations eligible?
Yes. For-profit organizations (other than small businesses) are eligible, and small businesses are also listed as eligible applicants.
Does the FOA explicitly encourage applications from specific institution types?
Yes. The description highlights a range of other eligible applicants, including Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISI).
Are tribal organizations eligible?
Yes. The opportunity includes Indian/Native American Tribal Governments that are not federally recognized among eligible applicants.
Are federal agencies eligible to apply?
Yes. Eligible federal agencies are included in the list of eligible applicants.
Are faith-based or community-based organizations eligible?
Yes. Faith-based or community-based organizations are explicitly listed as eligible applicants.
Are regional organizations and U.S. territories eligible?
Yes. Regional organizations and U.S. territories or possessions are included as eligible applicants.
Are non-U.S. (foreign) organizations allowed to apply?
Yes. The description states that non-U.S. entities (foreign organizations) are eligible, indicating NIH interest in a diverse applicant pool and research settings.
What is the Funding Opportunity Number and CFDA number?
The Funding Opportunity Number is PA-18-383. The CFDA number provided is 93.361.
When was this opportunity created?
The creation date listed is November 21, 2017.
What is the closing date shown in the provided information?
The provided listing includes an original closing date of January 7, 2021.
Is the maximum award amount (award ceiling) provided?
No. The award ceiling is not specified in the provided information.
Is the expected number of awards provided?
No. The expected number of awards is not specified in the provided information.
Where should applicants look for budget expectations and project period norms?
Based on the description, applicants would typically consult the full FOA text and NIH institute-specific guidance for details such as budget expectations, project period norms, and programmatic priorities.
What overall type of impact is NIH aiming for with this opportunity?
Overall, the opportunity is positioned to fund rigorous research that clarifies what effective family-centered self-management looks like, how to measure it, how to improve it, and how to support families as active partners in long-term chronic disease care.
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