Opportunity Information: Apply for PA 17 014
The grant opportunity titled "Addressing Unmet Needs in Persons with Dementia to Decrease Behavioral Symptoms and Improve Quality of Life (R01)" (Funding Opportunity Number PA-17-014) is a discretionary NIH research grant designed to push forward clinical research that targets behavioral and psychological symptoms of dementia (often abbreviated as BPSD). In practical terms, the FOA is focused on studies that do more than just describe agitation, aggression, anxiety, depression, wandering, sleep disruption, psychosis, or other distressing symptoms that can occur in dementia. Instead, it emphasizes research that connects those behavioral symptoms to underlying unmet needs in the person with dementia, especially needs that are physical (for example pain, infection, hunger, constipation, medication side effects, sensory impairment), social (isolation, lack of meaningful engagement, caregiver interaction patterns), or environmental (overstimulation, understimulation, confusing layouts, poor lighting, noise, unsafe or unfamiliar settings). The core idea is that many behavioral symptoms may be expressions of discomfort or unmet needs, and that identifying and addressing those needs can reduce symptoms while improving day-to-day quality of life.
This FOA uses the NIH R01 mechanism, which typically supports hypothesis-driven, investigator-initiated clinical research of meaningful scope and duration. The funding activity category is listed under Education and Health, and the CFDA number associated with the program is 93.361. The sponsoring agency is the National Institutes of Health, signaling that the scientific expectations align with NIH standards for rigor, ethical conduct, and clinical relevance. The announcement was created on 2016-10-18, and the original closing date shown is 2018-01-24, which places it in a specific submission window historically (anyone interested would still need to verify whether the opportunity is currently active, reissued, or replaced by a newer announcement).
From a project standpoint, applications would be expected to propose clinical research that can plausibly show how assessing and meeting unmet needs changes BPSD outcomes and improves quality of life. That can include developing or testing interventions that systematically identify unmet needs and respond with tailored strategies, measuring behavioral outcomes and patient-centered outcomes, and examining the pathways linking unmet needs to symptom expression. Because the FOA explicitly highlights physical, social, and environmental unmet needs, strong proposals would typically make those domains measurable and actionable, rather than treating them as vague background factors. In other words, the emphasis is not only on reducing problem behaviors, but on improving well-being by addressing root causes that may be modifiable in real-world care settings.
Eligibility is broad and includes many standard domestic applicant types such as state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations (other than federally recognized tribal governments); nonprofits with and without 501(c)(3) status (excluding higher education institutions in those categories); for-profit organizations other than small businesses; small businesses; and an "other" category that signals additional entities may qualify depending on NIH policy and the specific announcement terms. The FOA also calls out additional eligible applicants, reflecting an intent to include organizations serving diverse and historically underserved communities and settings where dementia care occurs. These specifically include Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); Indian/Native American Tribal Governments (other than federally recognized); faith-based or community-based organizations; eligible federal agencies; regional organizations; U.S. territories or possessions; and non-domestic (non-U.S.) entities, meaning foreign organizations can be eligible as well.
Overall, the opportunity is aimed at generating clinically useful evidence that links behavioral symptoms in dementia to unmet needs and tests strategies to recognize and address those needs in order to reduce distress, improve functioning, and raise quality of life for people living with dementia. It is structured to attract a wide range of applicants and settings, from academic health systems to community organizations and institutions serving specific populations, which matches the reality that dementia care and the management of BPSD happen across many environments, not just specialized clinics.Apply for PA 17 014
- The National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Addressing Unmet Needs in Persons with Dementia to Decrease Behavioral Symptoms and Improve Quality of Life (R01)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.361.
- This funding opportunity was created on 2016-10-18.
- Applicants must submit their applications by 2018-01-24. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: Addressing Unmet Needs in Persons with Dementia to Decrease Behavioral Symptoms and Improve Quality of Life (R01) - PA-17-014
What is the title and funding opportunity number for this grant?
The opportunity is titled "Addressing Unmet Needs in Persons with Dementia to Decrease Behavioral Symptoms and Improve Quality of Life (R01)" and the Funding Opportunity Number is PA-17-014.
Which agency is sponsoring this funding opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
What type of grant mechanism does this opportunity use?
This announcement uses the NIH R01 mechanism, which typically supports hypothesis-driven, investigator-initiated clinical research with meaningful scope and duration.
What is the main purpose of this FOA?
The FOA is designed to advance clinical research that targets behavioral and psychological symptoms of dementia (BPSD) by linking those symptoms to underlying unmet needs in the person with dementia and testing approaches that identify and address those needs to reduce symptoms and improve quality of life.
What are behavioral and psychological symptoms of dementia (BPSD) in the context of this FOA?
BPSD refers to distressing symptoms that can occur in dementia, such as agitation, aggression, anxiety, depression, wandering, sleep disruption, psychosis, and related behavioral or psychological changes.
Is this FOA focused on describing symptoms or testing solutions?
The emphasis is on research that goes beyond describing BPSD. The FOA prioritizes studies that connect symptoms to unmet needs and evaluate strategies or interventions that assess and address those needs to improve outcomes.
What is meant by "unmet needs" in a person with dementia?
In this FOA, unmet needs are potential underlying drivers of behavioral symptoms. They may be physical, social, or environmental factors that create discomfort, distress, confusion, or reduced well-being and can potentially be identified and modified.
What kinds of physical unmet needs are highlighted?
Examples include pain, infection, hunger, constipation, medication side effects, and sensory impairment.
What kinds of social unmet needs are highlighted?
Examples include social isolation, lack of meaningful engagement, and caregiver interaction patterns that may contribute to distress or symptom expression.
What kinds of environmental unmet needs are highlighted?
Examples include overstimulation, understimulation, confusing layouts, poor lighting, noise, and unsafe or unfamiliar settings.
What is the core idea behind linking unmet needs to BPSD?
The FOA is grounded in the concept that many behavioral symptoms may be expressions of discomfort or unmet needs, and that systematically identifying and addressing those needs can reduce symptoms while improving day-to-day quality of life.
What types of projects are expected to be competitive under this FOA?
Applications are expected to propose clinical research that can plausibly demonstrate how assessing and meeting unmet needs changes BPSD outcomes and improves quality of life. This may include developing or testing interventions that identify unmet needs and respond with tailored strategies, measuring behavioral and patient-centered outcomes, and examining pathways linking unmet needs to symptom expression.
Does the FOA require unmet needs to be measurable and actionable?
Yes. The FOA emphasizes making physical, social, and environmental unmet need domains measurable and actionable, rather than treating them as vague context.
What outcomes does the FOA emphasize?
The FOA emphasizes reducing behavioral symptoms and improving well-being and quality of life by addressing root causes that may be modifiable in real-world care settings.
What is the funding activity category listed for this opportunity?
The funding activity category is listed under Education and Health.
What CFDA number is associated with this program?
The CFDA number associated with the program is 93.361.
When was this announcement created?
The announcement was created on 2016-10-18.
What is the original closing date shown for this FOA?
The original closing date shown is 2018-01-24.
Is this opportunity still active?
The information provided places the FOA in a historical submission window. Anyone interested would need to verify whether it is currently active, has been reissued, or has been replaced by a newer announcement.
Who can apply (general eligibility)?
Eligibility is broad and includes many domestic applicant types, including state, county, city or township governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities and Indian housing authorities; Native American tribal organizations (other than federally recognized tribal governments); nonprofits with and without 501(c)(3) status (excluding higher education institutions in those categories); for-profit organizations other than small businesses; small businesses; and an "other" category that may include additional entities depending on NIH policy and the specific announcement terms.
Are institutions serving specific populations explicitly encouraged or included in eligibility?
Yes. Additional eligible applicants called out include Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); Indian/Native American Tribal Governments (other than federally recognized); and faith-based or community-based organizations.
Are federal agencies eligible to apply?
Yes, eligible federal agencies are specifically listed among additional eligible applicants.
Are regional organizations eligible to apply?
Yes, regional organizations are specifically listed among additional eligible applicants.
Are U.S. territories or possessions eligible to apply?
Yes, U.S. territories or possessions are specifically listed among additional eligible applicants.
Are non-U.S. (foreign) organizations eligible to apply?
Yes. The FOA indicates that non-domestic (non-U.S.) entities may be eligible, meaning foreign organizations can qualify.
What kinds of settings does this FOA appear intended to reach?
The opportunity is structured to attract a wide range of applicants and settings, including academic health systems and community organizations, reflecting that dementia care and BPSD management occur across many environments, not only specialized clinics.
Does the FOA indicate expectations around scientific rigor and ethical conduct?
Because it is an NIH opportunity, the expectations align with NIH standards for rigor, ethical conduct, and clinical relevance.
What is the practical focus of the research encouraged by this FOA?
The practical focus is to generate clinically useful evidence that links behavioral symptoms in dementia to unmet needs and tests strategies to recognize and address those needs to reduce distress, improve functioning, and improve quality of life for people living with dementia.
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Applicants also applied for:
Applicants who have applied for this opportunity (PA 17 014) also looked into and applied for these:
| Funding Opportunity |
|---|
| Addressing Unmet Needs in Persons with Dementia to Decrease Behavioral Symptoms and Improve Quality of Life (R21) Apply for PA 17 013 Funding Number: PA 17 013 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Self-Management Interventions and Technologies to Sustain Health and Optimize Functional Capabilities (R21) Apply for PA 17 011 Funding Number: PA 17 011 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Improving Individual and Family Outcomes through Continuity and Coordination of Care in Hospice (R01) Apply for PA 17 016 Funding Number: PA 17 016 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Palliative Care Needs of Individuals with Advanced Rare Diseases and Their Family Caregivers (R01) Apply for PA 17 018 Funding Number: PA 17 018 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Palliative Care Needs of Individuals with Rare Advanced Diseases and Their Family Caregivers (R21) Apply for PA 17 017 Funding Number: PA 17 017 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Use of Technology to Enhance Patient Outcomes and Prevent Illness (R01) Apply for PA 17 010 Funding Number: PA 17 010 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Nicotinic Immune Modulation in the Presence of HIV-1 Infection (R01) Apply for RFA DA 17 020 Funding Number: RFA DA 17 020 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Improving Quality of Care and Quality of Life for Persons with Alzheimers Disease and Related Dementias at the End of Life (R01) Apply for PAS 17 027 Funding Number: PAS 17 027 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Improving Quality of Care and Quality of Life for Persons with Alzheimers Disease and Related Dementias at the End of Life (R03) Apply for PAS 17 026 Funding Number: PAS 17 026 Agency: National Institutes of Health Category: Education, Health Funding Amount: $50,000 |
| NCI Research Specialist (Core-based Scientist) Award (R50) Apply for PAR 17 050 Funding Number: PAR 17 050 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Research Specialist (laboratory-based Scientist) Award (R50) Apply for PAR 17 049 Funding Number: PAR 17 049 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Phylodynamic Tracking of HIV Transmission (R01) Apply for PAR 17 048 Funding Number: PAR 17 048 Agency: National Institutes of Health Category: Education, Health Funding Amount: $499,999 |
| Innovative Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R21) Apply for RFA CA 17 010 Funding Number: RFA CA 17 010 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| National Cancer Institute Youth Enjoy Science Research Education Program (R25) Apply for PAR 17 059 Funding Number: PAR 17 059 Agency: National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| Promoting Caregiver Health Using Self-Management (R01) Apply for PA 17 062 Funding Number: PA 17 062 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Limited Competition: Cancer Immunotherapy Trials Network (CITN)(UM1) Apply for RFA CA 16 501 Funding Number: RFA CA 16 501 Agency: National Institutes of Health Category: Education, Health Funding Amount: $3,000,000 |
| Oral Anticancer Agents: Utilization, Adherence, and Health Care Delivery (R21) Apply for PA 17 061 Funding Number: PA 17 061 Agency: National Institutes of Health Category: Education, Health Funding Amount: $200,000 |
| Oral Anticancer Agents: Utilization, Adherence, and Health Care Delivery (R01) Apply for PA 17 060 Funding Number: PA 17 060 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Transition Career Development Award to Promote Diversity (K22) Apply for PAR 17 069 Funding Number: PAR 17 069 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Optimizing the HIV Care Continuum for Substance Abusing Populations at High-Risk and/or Living with HIV (R01) Apply for RFA DA 17 024 Funding Number: RFA DA 17 024 Agency: National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
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