Opportunity Information: Apply for PAR 16 361
The Research Initiative for Scientific Enhancement (RISE) (R25) is a National Institutes of Health (NIH) research education grant opportunity designed to support structured educational activities that align with NIH mission areas. This program uses the R25 research education mechanism, which is meant to strengthen research training and educational experiences rather than fund a traditional, stand-alone research project. In this specific announcement, the program is associated with the National Institute of General Medical Sciences (NIGMS), and its central purpose is to build and broaden the pipeline of future scientists by improving research education opportunities.
A major emphasis of the RISE program is workforce diversity. The stated overarching goal is to support educational activities that enhance the diversity of the biomedical, behavioral, and clinical research workforce. In practice, this means applicant institutions are expected to propose program activities that help students and trainees from groups that are underrepresented in the biomedical sciences gain meaningful exposure to research, develop stronger scientific skills, and become better positioned to pursue advanced training and research careers. Typical R25-style activities often include mentored research experiences, skills-building workshops, career development and graduate school preparation, curriculum enhancements, and structured mentoring networks, all organized around clear objectives and measurable outcomes.
Eligibility is oriented toward U.S.-based higher education institutions and certain designated institution types. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and additional eligible organizations as outlined in the full Funding Opportunity Announcement (FOA). The opportunity explicitly calls out several institution categories as eligible, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), and Tribally Controlled Colleges and Universities (TCCUs). These categories align with the program focus on expanding access and strengthening research education capacity at institutions that serve significant numbers of students from underrepresented backgrounds.
Foreign participation is clearly restricted. Non-domestic (non-U.S.) entities are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible. In addition, foreign components, as defined by the NIH Grants Policy Statement, are not allowed under this announcement. In other words, the program is intended to be planned, managed, and implemented entirely within eligible U.S.-based organizational structures, and applicants should not propose project components that meet NIH definitions of foreign components.
From the administrative details provided, the funding opportunity title is "Research Initiative for Scientific Enhancement (RISE) (R25)" with the funding opportunity number PAR-16-361. It is categorized as a discretionary grant program under the health funding activity category, with CFDA number 93.859, and the sponsoring agency is the National Institutes of Health. The opportunity record shows a creation date of 2016-07-08 and an original closing date of 2018-05-25. The award ceiling and expected number of awards are not specified in the provided summary fields, which usually means applicants must consult the FOA for budget limits, anticipated award counts, project period expectations, and any institute-specific constraints.
Overall, this opportunity is best understood as a capacity-building and student-development program: it supports institutions in creating or strengthening research education structures that improve preparation and progression for aspiring scientists, with a strong, explicit priority on increasing diversity in the biomedical research workforce. For full requirements, including allowable activities, participant eligibility, application components, budget rules, and review criteria, applicants are directed to the FOA itself, since those details govern what NIH will consider responsive and fundable.Apply for PAR 16 361
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Research Initiative for Scientific Enhancement (RISE) (R25)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.859.
- This funding opportunity was created on 2016-07-08.
- Applicants must submit their applications by 2018-05-25. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Public and State controlled institutions of higher education, Private institutions of higher education, Others.
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Frequently Asked Questions (FAQs): Research Initiative for Scientific Enhancement (RISE) (R25)
1) What is the RISE (R25) program?
The Research Initiative for Scientific Enhancement (RISE) (R25) is a National Institutes of Health (NIH) research education grant opportunity that supports structured educational activities aligned with NIH mission areas. It uses the R25 research education mechanism, which is designed to strengthen research training and educational experiences rather than fund a traditional, stand-alone research project.
2) Which NIH institute is associated with this specific RISE announcement?
This announcement is associated with the National Institute of General Medical Sciences (NIGMS).
3) What is the main purpose of this funding opportunity?
The central purpose is to build and broaden the pipeline of future scientists by improving research education opportunities at eligible institutions.
4) How does RISE relate to workforce diversity?
A major emphasis of RISE is workforce diversity. The overarching goal is to support educational activities that enhance the diversity of the biomedical, behavioral, and clinical research workforce, particularly by improving research education opportunities for individuals from groups underrepresented in the biomedical sciences.
5) What kinds of activities does an R25 research education program typically support?
Based on the description provided, typical R25-style activities often include mentored research experiences, skills-building workshops, career development and graduate school preparation, curriculum enhancements, and structured mentoring networks. These activities are generally organized around clear objectives and measurable outcomes.
6) Is this grant intended to fund a traditional research project?
No. The R25 mechanism is intended to strengthen research training and educational experiences, not to fund a traditional, stand-alone research project.
7) Who is eligible to apply?
Eligibility is oriented toward U.S.-based higher education institutions and certain designated institution types. Eligible applicants include public and state-controlled institutions of higher education, private institutions of higher education, and additional eligible organizations as outlined in the full Funding Opportunity Announcement (FOA).
8) Which institution categories are explicitly called out as eligible?
The opportunity explicitly identifies the following categories as eligible: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); and Tribally Controlled Colleges and Universities (TCCUs).
9) Why are certain institution categories highlighted in the eligibility information?
These categories align with the program focus on expanding access and strengthening research education capacity at institutions that serve significant numbers of students from underrepresented backgrounds.
10) Are non-U.S. (foreign) organizations eligible to apply?
No. Non-domestic (non-U.S.) entities are not eligible to apply under this announcement.
11) Can a U.S. organization include a non-domestic component in its application?
No. Non-domestic components of U.S. organizations are also not eligible under this announcement.
12) Are foreign components allowed in this program?
No. Foreign components, as defined by the NIH Grants Policy Statement, are not allowed under this announcement. The program is intended to be planned, managed, and implemented entirely within eligible U.S.-based organizational structures.
13) What is the Funding Opportunity Number for this program?
The Funding Opportunity Number is PAR-16-361.
14) What is the official funding opportunity title?
The title is "Research Initiative for Scientific Enhancement (RISE) (R25)".
15) Which federal agency sponsors this opportunity?
The sponsoring agency is the National Institutes of Health (NIH).
16) What is the CFDA number listed for this opportunity?
The CFDA number listed is 93.859.
17) How is this opportunity categorized in the provided administrative summary?
It is categorized as a discretionary grant program under the health funding activity category.
18) What are the creation date and the original closing date shown in the record?
The record shows a creation date of 2016-07-08 and an original closing date of 2018-05-25.
19) Is the award ceiling provided in the summary information?
No. The award ceiling is not specified in the provided summary fields, which typically means the applicant should consult the FOA for budget limits and related constraints.
20) Is the expected number of awards provided in the summary information?
No. The expected number of awards is not specified in the provided summary fields. Applicants are directed to the FOA for anticipated award counts and any institute-specific constraints.
21) Where should applicants look for the most authoritative requirements and rules?
Applicants should consult the full Funding Opportunity Announcement (FOA) for the governing details, including allowable activities, participant eligibility, application components, budget rules, project period expectations, and review criteria.
22) What is the overall way to think about what RISE funds?
Overall, this opportunity is best understood as a capacity-building and student-development program. It supports institutions in creating or strengthening research education structures that improve preparation and progression for aspiring scientists, with an explicit priority on increasing diversity in the biomedical research workforce.
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| Resource-Related Research Projects for Development of Animal Models and Related Materials (R24) Apply for PAR 16 369 Funding Number: PAR 16 369 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Development of the Gabriella Miller Kids First Pediatric Data Resource Center (U2C) Apply for RFA RM 16 010 Funding Number: RFA RM 16 010 Agency: National Institutes of Health Category: Health Funding Amount: $2,000,000 |
| Phenotypic and Functional Characterization of ApoE2 to Inform Translation Strategies for Aging-Related Conditions (R21) Apply for PAR 16 371 Funding Number: PAR 16 371 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Phenotypic and Functional Characterization of ApoE2 to Inform Translation Strategies for Aging-Related Conditions (R01) Apply for PAR 16 370 Funding Number: PAR 16 370 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Exploratory/Developmental Investigations on Primary Immunodeficiency Diseases (R21) Apply for PA 16 373 Funding Number: PA 16 373 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| Small Grants on Primary Immunodeficiency Diseases (R03) Apply for PA 16 372 Funding Number: PA 16 372 Agency: National Institutes of Health Category: Health Funding Amount: $50,000 |
| Predictors and Determinants of Age-Related Changes in Resiliencies to Physical Stressors in Humans (UH2/UH3) Apply for RFA AG 17 014 Funding Number: RFA AG 17 014 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| T1 Translational Research on Aging: Small Business Innovation Awards (R43/R44) Apply for PAR 16 375 Funding Number: PAR 16 375 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| T2 Translational Research on Aging: Small Business Innovation Awards (R43/R44) Apply for PAR 16 376 Funding Number: PAR 16 376 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Clinical Centers for the NHLBI's Precision Interventions for Severe and/or Exacerbation Prone Asthma (PrecISE) Network (UG1) Apply for RFA HL 17 009 Funding Number: RFA HL 17 009 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Data and Modeling Coordination Center for the NHLBI's Precision Interventions for Severe and/or Exacerbation-Prone Asthma (PrecISE) Network (U24) Apply for RFA HL 17 010 Funding Number: RFA HL 17 010 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Research Innovations for Scientific Knowledge (RISK) for Musculoskeletal Diseases (R61/R33) Apply for RFA AR 17 009 Funding Number: RFA AR 17 009 Agency: National Institutes of Health Category: Health Funding Amount: $250,000 |
| Pre-Application: Research Innovation for Scientific Knowledge (RISK) for Musculoskeletal Diseases (X02) Apply for PAR 16 382 Funding Number: PAR 16 382 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Research Innovation for Scientific Knowledge (RISK) for Skin and Rheumatic Diseases (R61/R33) Apply for RFA AR 17 008 Funding Number: RFA AR 17 008 Agency: National Institutes of Health Category: Health Funding Amount: $250,000 |
| Pre-Application: Research Innovation for Scientific Knowledge (RISK) for Skin and Rheumatic Diseases (X02) Apply for PAR 16 381 Funding Number: PAR 16 381 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
| Elucidation of Mechanisms of Radiation-Induced Endovascular Injury and Development of Treatments / Mitigators for Radiation-Induced Endothelial Cell and Vascular Dysfunction (U01) Apply for RFA AI 16 053 Funding Number: RFA AI 16 053 Agency: National Institutes of Health Category: Health Funding Amount: $350,000 |
| Notice of Funding Opportunity - Public Affairs Section Small Grants Program - Solicitation of proposals from community-based, faith-based and civil society organizations working on the response to HIV/AIDS in Mozambique. Apply for PAS PEPFAR 01 2016 Funding Number: PAS PEPFAR 01 2016 Agency: U.S. Mission to Mozambique Category: Health Funding Amount: $25,000 |
| NIBIB Trailblazer Award for New and Early Stage Investigators (R21) Apply for PAR 16 390 Funding Number: PAR 16 390 Agency: National Institutes of Health Category: Health Funding Amount: $200,000 |
| NIMH Career Transition Award for Tenure-Track and Tenured Intramural Investigators (K22) Apply for PAR 16 389 Funding Number: PAR 16 389 Agency: National Institutes of Health Category: Health Funding Amount: Case Dependent |
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